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-acetyl-l-aspartate is an excellent substrate for aspartoacylase from human Mind (31). The kinetic parameters to the hydrolysis of 6 with NagA are detailed in Desk two This substrate is hydrolyzed in a noticeably speedier rate than is definitely the corresponding N
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Web page certain mutants link naga26 of NagA were made so as to confirm the roles of unique residues in substrate recognition and catalytic functionality. The metallic content material as well as the kinetic parameters to the mutants of NagA produced for this investigation are introduced in Desk four.
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